“With that, now we think we have generated that format of vaccine that they could be very effective. It could be relatively easy to manufacture and to apply,” Dr. Gambotto said. From a clinical standpoint, Dr. Falo says the microneedle array has many advantages. “So, this is an incredibly safe approach. There is no bleeding with this approach, there’s no pain because the needles are not long enough to reach the circulation or nerves,” said Dr. Falo. “In addition to that, the amounts of antigen that we’re using are so small that they don’t cause any adverse effects, in and of themselves.” Each of the 400 microneedles are the width of a human hair, and they are only a half a millimeter long. The whole thing is made of liquid sugar and mixed with the antigen doctors want to use in their vaccine. “When the microneedles are hard, they’re able to penetrate the outer layers of the skin. And, then, as they absorb moisture, they actually dissolve and release the antigen into the skin, so the needles are actually the vaccine,” Dr. Falo added. Dr. Falo hopes the next step is approval to take the microneedle array candidate to clinical trials, but says the most important thing is to find an answer. “The only competition here is the competition with the virus,” he said. “I think we’re all trying to work in the same direction. I think it’s better when we don’t compete with each other that we work together on this, and I think the virus is the real enemy here.”